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Clinical significance of para-aortic lymph node dissection and prognosis in ovarian cancer

Xianxian Li, Hui Xing, Lin Li, Yanli Huang, Min Zhou, Qiong Liu, Xiaomin Qin, Min He

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 96-100 doi: 10.1007/s11684-014-0316-4

Abstract:

Lymph node metastasis has an important effect on prognosis of patients with ovarian cancer.Moreover, the impact of para-aortic lymph node (PAN) removal on patient prognosis is still unclear.In group B, 13 cases were positive for lymph node metastasis.Our study suggested that the metastatic rate of lymph node is 40.0%.Consequently, in ovarian carcinoma cytoreductive surgery, resection of the para-aortic lymph node, which

Keywords： ovarian cancer     para-aortic lymph node     pelvic lymph node    

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Application progress of lymphography in oncology

Yang YU, Jibin LIU, Lixue YIN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 13-19 doi: 10.1007/s11684-009-0016-7

Abstract: Lymphography is often used for the diagnosis of lymphatic metastasis in oncology. Determination of lymphatic metastasis is extremely important for accurate cancer staging, which may directly guide the clinical therapeutic scheme. In recent years, the technology of lymphography has developed rapidly on the basis of traditional lymphography, with the appearance of computed tomography (CT) lymphography, nuclear magnetic resonance (MR) lymphography, contrast-enhanced lymphosonography, and so on; the diagnostic accuracy has also been improved. The imaging principles and methods of these various technologies of lymphography are reviewed in this paper, and their applications and significance in oncology are also discussed in detail.

Keywords： lymphography     lymphatic metastasis     sentinel lymph node biopsy    

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The value of ultrasound elastography in differential diagnosis of superficial lymph nodes

Yanrong ZHANG phD , Qing LV MD , Mingxing XIE MD , Feixiang XIANG phD , Chengfa LU BM , Tianwei YAN BM , Wei LI BM , Hui XU BM , Yan HUANG BM , Yehua YIN BM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 368-374 doi: 10.1007/s11684-009-0063-0

Abstract: evaluated the value of ultrasound elastography in differentiating the benign and malignant superficial lymphA total of 112 subjects, including 82 patients with enlarged lymph nodes and 30 healthy volunteers, wereThe elasticity of the lymph nodes was quantitatively measured and defined as stiffness value.The stiffness values of two indeterminate benign lymph nodes, the elastrographic findings of which wereThe elastographic findings of 10 malignant lymph nodes were also classified as pattern 2 or 3.

Keywords： ultrasound elastography     lymph node     power Doppler sonography    

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Correlation of Twist upregulation and senescence bypass during the progression and metastasis of cervical cancer

Tian Wang, Yan Li, Abidan Tuerhanjiang, Wenwen Wang, Zhangying Wu, Ming Yuan, Shixuan Wang

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 106-112 doi: 10.1007/s11684-014-0307-5

Abstract:

Cervical carcinoma is associated with high propensity for local invasion and lymph node metastasisThe strong positive expressions of Twist in the SCC groups with or without lymph node metastasis were

Keywords： cervical cancer     senescence     Twist     CBX3     lymph node metastasis    

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Adjuvant chemotherapy versus adjuvant concurrent chemoradiotherapy after radical surgery for early-stage cervical cancer: a randomized, non-inferiority, multicenter trial

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 93-104 doi: 10.1007/s11684-021-0892-z

Abstract: We conducted a prospective study to assess the non-inferiority of adjuvant chemotherapy alone versus adjuvant concurrent chemoradiotherapy (CCRT) as an alternative strategy for patients with early-stage (FIGO 2009 stage IB–IIA) cervical cancer having risk factors after surgery. The condition was assessed in terms of prognosis, adverse effects, and quality of life. This randomized trial involved nine centers across China. Eligible patients were randomized to receive adjuvant chemotherapy or CCRT after surgery. The primary end-point was progression-free survival (PFS). From December 2012 to December 2014, 337 patients were subjected to randomization. Final analysis included 329 patients, including 165 in the adjuvant chemotherapy group and 164 in the adjuvant CCRT group. The median follow-up was 72.1 months. The three-year PFS rates were both 91.9%, and the five-year OS was 90.6% versus 90.0% in adjuvant chemotherapy and CCRT groups, respectively. No significant differences were observed in the PFS or OS between groups. The adjusted HR for PFS was 0.854 (95% confidence interval 0.415–1.757; P = 0.667) favoring adjuvant chemotherapy, excluding the predefined non-inferiority boundary of 1.9. The chemotherapy group showed a tendency toward good quality of life. In comparison with post-operative adjuvant CCRT, adjuvant chemotherapy treatment showed non-inferior efficacy in patients with early-stage cervical cancer having pathological risk factors. Adjuvant chemotherapy alone is a favorable alternative post-operative treatment.

Keywords： chemotherapy     cervical cancer     lymph node metastasis     concurrent chemoradiotherapy     quality of life    

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The evolution of surgical and medical treatment of aortic root aneurysm

Xu Yu Jin,Li Yuan,Mario Petrou,John R. Pepper

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 427-432 doi: 10.1007/s11684-014-0385-4

Abstract:

Since first report of aortic root replacement in 1968, the surgical risk and long term outcome ofpatients with aortic root aneurysm have been continuously improving.

Keywords： aortic root aneurysm     aortic root replacement     valve sparing root replacement     personalised external aortic    

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Evaluation of the harmonic scalpel in open surgery for abdominal aortic aneurysm

Zeyu Wu, Zhe Chen, Lin Peng

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 85-88 doi: 10.1007/s11684-012-0174-x

Abstract: however, no evidence showing the advantages of using the harmonic scalpel in complicated abdominal aortic

Keywords： abdominal aortic aneurysm     harmonic scalpel     minimally invasive    

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engineering in the construction of numerical simulation oriented patient-specific model of stented aortic

Xianlong MENG, Wenyu FU, Yun ZHANG, Aike QIAO,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 3,   Pages 328-335 doi: 10.1007/s11465-010-0026-9

Abstract: the approaches to the reconstruction of a numerical simulation-oriented patient-specific model for aorticBased on a surface model of aortic arch aneurysm in STL format, reverse engineering concept was appliedmodel using CAD software Geomagic and Pro/E, and a simplified model of stent for the intervention of aorticbe meshed according to particular requirements in each volume; the finite element model of stented aorticThe approaches of modeling were applicable not only for aortic arch aneurysm, but also for similar model

Keywords： reverse engineering     aortic arch aneurysm     surface model     meshing     finite element model    

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Identification of variants associated with sporadic thoracic aortic dissection: a case--control study

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 438-447 doi: 10.1007/s11684-020-0826-1

Abstract: Thoracic aortic dissection (TAD) without familial clustering or syndromic features is known as sporadicFurther bioinformatics analysis showed that COL3A1 was highly expressed in dissected aortic tissues

Keywords： sporadic thoracic aortic dissection     exome sequencing     gene COL3A1     case–control study     extracellular    

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Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience

Maryanne Caruana,Mary N. Sheppard,Wei Li

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 419-426 doi: 10.1007/s11684-014-0383-6

Abstract:

Aneurysmal dilatation of the aortic sinuses of Valsalva has been most extensively documented in theIn conclusion, there are differences in management of aortic dilatation in Marfan syndrome and congenital

Keywords： sinus of Valsalva aneurysms     Marfan syndrome     aortic dissection    

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Right coronary occlusion following transcatheter aortic valve implantation: two case reports

Gang Zhang,Jun Luo,Guo Chen

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 351-355 doi: 10.1007/s11684-016-0465-8

Abstract:

This paper discusses two male patients with severe aortic stenosis, whose right coronary arteries(RCA) were completely occluded during transcatheter aortic valve implantation (TAVI), leading to fatalBoth patients were admitted for “severe aortic stenosis,” and TAVIs were performed.

Keywords： aortic stenosis     transcatheter aortic valve implantation     right coronary occlusion     cardiac group    

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in improving left ventricular remodelling and clinical outcome following surgical and trans-catheter aortic

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 416-437 doi: 10.1007/s11684-021-0852-7

Abstract: Over the last half century, surgical aortic valve replacement (SAVR) has evolved to offer a durable andThe latter has become more challenging among elderly patients, particularly following trans-catheter aorticEarly intervention in asymptomatic aortic stenosis or regurgitation along with individualised managementPhysiological pacing via the His-Purkinje system for conduction abnormalities, further reduction in para-valvularaortic regurgitation along with therapy of angiotensin receptor blockade will improve patient outcome

Keywords： surgical aortic valve replacement     trans-catheter aortic valve implantation     left ventricular hypertrophy    

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Aortic aneurysm and chronic disseminated intravascular coagulation: a retrospective study of 235 patients

Yun Zhang,Chen Li,Min Shen,Bao Liu,Xuejun Zeng,Ti Shen

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 62-67 doi: 10.1007/s11684-017-0498-7

Abstract:

Chronic disseminated intravascular coagulation (DIC) is a rare but devastating complication of aortic

Keywords： aortic aneurysm     disseminated intravascular coagulation     anticoagulation therapy    

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Histopathological study of congenital aortic valve malformations in 32 children

HUANG Ping, WANG Hongwei, LI Yanping, CHENG Peixuan, LIU Qingjun, ZHANG Zhenlu, LIU Jianying

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 74-78 doi: 10.1007/s11684-007-0015-5

Abstract: The histopathological characteristics of congenital aortic valve malformations in children were investigatedAll the native surgically excised aortic valves from 32 pediatric patients suffering from symptomaticaortic valve dysfunction due to congenital aortic valve malformations between January 2003 and DecemberThere were five cases of aortic stenosis (AS, 15.62%), 25 cases of aortic insufficiency (AI, 78.13%)Aortic insufficiency is more common in children with congenital aortic valve malformations.
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Spatial embedded reinforcement of 20-node block element for analysis PC bridges

LONG Peiheng, DU Xianting, CHEN Weizhen

Frontiers of Structural and Civil Engineering 2008, Volume 2, Issue 3,   Pages 274-280 doi: 10.1007/s11709-008-0039-1

Abstract: It is an effective approach that the no-node loads are diverted from the tendons to the adjacent concrete

Keywords： arithmetic analysis     calculation     prestressed reinforcement     mechanical     arbitrary    

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Title Author Date Type Operation

Clinical significance of para-aortic lymph node dissection and prognosis in ovarian cancer

Xianxian Li, Hui Xing, Lin Li, Yanli Huang, Min Zhou, Qiong Liu, Xiaomin Qin, Min He

Journal Article

Application progress of lymphography in oncology

Yang YU, Jibin LIU, Lixue YIN

Journal Article

The value of ultrasound elastography in differential diagnosis of superficial lymph nodes

Yanrong ZHANG phD , Qing LV MD , Mingxing XIE MD , Feixiang XIANG phD , Chengfa LU BM , Tianwei YAN BM , Wei LI BM , Hui XU BM , Yan HUANG BM , Yehua YIN BM ,

Journal Article

Correlation of Twist upregulation and senescence bypass during the progression and metastasis of cervical cancer

Tian Wang, Yan Li, Abidan Tuerhanjiang, Wenwen Wang, Zhangying Wu, Ming Yuan, Shixuan Wang

Journal Article

Adjuvant chemotherapy versus adjuvant concurrent chemoradiotherapy after radical surgery for early-stage cervical cancer: a randomized, non-inferiority, multicenter trial

Journal Article

The evolution of surgical and medical treatment of aortic root aneurysm

Xu Yu Jin,Li Yuan,Mario Petrou,John R. Pepper

Journal Article

Evaluation of the harmonic scalpel in open surgery for abdominal aortic aneurysm

Zeyu Wu, Zhe Chen, Lin Peng

Journal Article

engineering in the construction of numerical simulation oriented patient-specific model of stented aortic

Xianlong MENG, Wenyu FU, Yun ZHANG, Aike QIAO,

Journal Article

Identification of variants associated with sporadic thoracic aortic dissection: a case--control study

Journal Article

Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience

Maryanne Caruana,Mary N. Sheppard,Wei Li

Journal Article

Right coronary occlusion following transcatheter aortic valve implantation: two case reports

Gang Zhang,Jun Luo,Guo Chen

Journal Article

in improving left ventricular remodelling and clinical outcome following surgical and trans-catheter aortic

Journal Article

Aortic aneurysm and chronic disseminated intravascular coagulation: a retrospective study of 235 patients

Yun Zhang,Chen Li,Min Shen,Bao Liu,Xuejun Zeng,Ti Shen

Journal Article

Histopathological study of congenital aortic valve malformations in 32 children

HUANG Ping, WANG Hongwei, LI Yanping, CHENG Peixuan, LIU Qingjun, ZHANG Zhenlu, LIU Jianying

Journal Article

Spatial embedded reinforcement of 20-node block element for analysis PC bridges

LONG Peiheng, DU Xianting, CHEN Weizhen

Journal Article